Tolerance is a good thing in most aspects of life. But when it comes to the immune system, artificially juicing up the body to create antibodies with long-term tolerance to a pathogen is a recipe for disaster. Amid thousands of papers on COVID and the vaccines, a new German paper published in Science Immunology implies that the Pfizer shots (and possibly other mRNA spike protein shots) cause the immune system to misfire, thereby creating an endless feedback loop of viral immune escape, perpetuating the pandemic in the macro, and creating immune suppression for the individuals who received them.
BY DANIEL HOROWITZ FOR CONSERVATIVE REVIEW
The vexing question of 2023 is why the virus is even still with us to this day. Why is it that so many countries in the Pacific Rim that did so well in 2020 and 2021 now have a bigger problem with less virulent strains of COVID? Why does it appear the pandemic will never end and so many people continue to get the virus multiple times? None of this is normal.
Wherever you turn, the most vaccinated countries are not only experiencing rampant side effects from the shots, but worse outcomes from COVID itself following their endless booster campaigns.
But even more telling than an epidemiological comparison of one nation to another is a comparison of outcomes within nations themselves between pre- and post-vaccination/booster campaign. Prior to the mass vaccination, two parts of the world largely escaped excess deaths from the virus: continental Africa and the Pacific Rim nations. Yet whereas Africa flatlined in terms of COVID deaths throughout 2021-2022, countries like Japan only experienced meaningful numbers of deaths after the mass vaccination program.
Japan is experiencing progressively worse death curves, which only began after everyone (particularly seniors) was boosted, even though Omicron is less pathogenic than the earlier strains. Japan is also the current world leader in cases per million.
Australia is a similar story… and contrast these two countries to Nigeria, the most populous country in Africa.
Indeed, Chile now has the most deaths per capita in South America, even though the country already suffered a substantial number of deaths and should be done with the pandemic. Nigeria and the rest of Africa indeed are done with the pandemic, and the U.S., which has an average booster rate, is somewhere in the middle in terms of current COVID rates.
So, this is about a lot more than “oh, the vaccines don’t stop transmission.” They appear to proliferate it and also to worsen clinical outcomes. But why?
A group of German researchers tested for which specific antibody levels spike at what time. Specifically, they tested the Pfizer shot against the AstraZeneca shot and discovered something very concerning. Increasingly over time, and particularly with three doses of Pfizer, the immune response switched from the more neutralizing IgG1 and IgG3 antibodies to the non-neutralizing “tolerating” IgG4 antibodies:
High levels of neutralizing SARS-CoV-2-antibodies are an important component of vaccine-induced immunity. Shortly after the initial two mRNA vaccine doses, the IgG response mainly consists of the pro-inflammatory subclasses IgG1 and IgG3. Here, we report that several months after the second vaccination, SARS-CoV-2-specific antibodies were increasingly composed of non-inflammatory IgG4, which were further boosted by a third mRNA vaccination and/or SARS-CoV-2 variant breakthrough infections. IgG4 antibodies among all spike-specific IgG antibodies rose on average from 0.04% shortly after the second vaccination to 19.27% late after the third vaccination. This induction of IgG4 antibodies was not observed after homologous or heterologous SARS-CoV-2 vaccination with adenoviral vectors [emphasis added].
Why is this so important?
Importantly, this class switch was associated with a reduced capacity of the spike-specific antibodies to mediate antibody-dependent cellular phagocytosis and complement deposition. Since Fc-mediated effector functions are critical for antiviral immunity, these findings may have consequences for the choice and timing of vaccination regimens using mRNA vaccines, including future booster immunizations against SARS-CoV-2 [emphasis added].
So not only do these shots fail to produce the first line of defense antibodies known as IgA in the mucosal, something we knew from day one, but even the blood-based antibodies are increasingly the wrong type. This problem seems to get worse over time and with more doses of the shot, which correlates perfectly with numerous studies showing negative efficacy increasing over time, with more doses, and how the vaccinated take longer to clear the virus.
This topic is both very dense and fascinating. You can find clear explanations of this study about IgG4 antibodies in layman’s terms here, here, and here. But the important outcome for us from a policy standpoint is understanding the deadly subterfuge that has been foisted upon 5.5 billion people of the world and how it will be used with many more novel vaccines coming down the pipeline. The medical establishment successfully convinced the world that a vaccine is nothing more than simply stimulating an antibody response and is something that can be done within days of discovering a virus. This is why they now seek to get vaccines approved not based on accurate clinical trials and clinical outcomes but on “immunobridging” – the measuring of antibody levels. Indeed, this is how they got the bivalent booster shots and the JYNNEOS monkeypox vaccine approved and how they plan to get future shots approved.
However, merely measuring antibody levels in the abstract is meaningless and potentially masks harms to the body. God designed our bodies to create the right sort of antibodies, in the right amount, at the right time, in the right place. Any fault in any of those factors can create auto-antibodies, Trojan horse antibodies (antibody dependent disease enhancement) or a misfiring of the immune system, which is some form of original antigenic sin or pathogenic priming that teaches the body to tolerate a specific strain of the virus or respond for a wrong strain. This is why vaccines take years to develop. And this is before we even discuss the fact that these shots are not even vaccines, but are gene therapies that code your body to produce a pathogenic spike that was the result of gain-of-function research and seems to potentially damage every organ system, particularly the cardiovascular system.
In the case of the COVID shots, what the German study discovered is that over time and with increased doses it actually trains your body to tolerate rather than fight the virus it was designed to destroy. The other class of blood-based antibodies are designed to neutralize pathogens; however, the IgG4 class was specifically designed to tolerate innocuous cells (that don’t reproduce) that it repeatedly contacts, such as pollen or peanut particles. They serve an important role and help ensure that people don’t respond with excessive inflammation to everyday encounters with pollen, but to see 20% of the antibody response to SARS-CoV-2 (it was as high as 42% in those experiencing infection after boosters) be something that tolerates it is astounding … and dangerous! In other words, whereas your IgG1 or IgG3 antibodies are like the SWAT team, your IgG4 antibodies are like social workers. You don’t want social workers responding to replicating pathogens like the SARS-CoV-2 spike.
The long-term implications of this study are still unclear, but like every earth-shattering finding, this one will not be studied by governments. If this shot is really upregulating an IgG4 response for most of the population, it could easily explain why herd immunity is out the window with SARS-CoV-2. It’s literally teaching the body to not only respond to the wrong pathogen but to tolerate its existence and not remember to fight it. Also, what does this mean long-term for people who don’t create pro-inflammatory antibodies to defend against pathogens? What sort of damage is being done by not having the virus sufficiently neutralized before it invades the system so deeply?
As Kilian Schober, one of the authors of the study, notes (after calling our interpretation of the study too “simplistic”),”Our findings do, however, raise some questions about how to proceed.” But in the past, we used to answer those questions before experimenting on humans, not begin to raise them (and then never answer them) after 5.5 billion people were already injected with the product.
- Well, here’s the medical facts that entirely explain why people with more shots get more covid.
I’ve been paying attention to this possibility for a while but until the study work came out that proved it all there was is speculation. ADE (“Antibody dependent enhancement”) is a fairly poorly-understood thing; most people believe it is confined to making a particular infection more serious than it would otherwise be. Of course having it occur when it otherwise would not fits that quite-nicely, but isn’t what people tend to think about.
Now, unfortunately, we have the evidence. Here’s the salient graph and lots of discussion which I’ll try to recap for you here:
Let me explain this one for you because it makes very clear what’s going on. There are multiple sub-types of IgG antibodies. IgG are the last ones that show up; IgA typically is in the mucosa of the nose, and is a “front line” of defense if you will. IgM shows up second; it generally is gone about two weeks or so after you recover. IgG is the “long term” antibody recognition but it has multiple subtypes.
This is very important for human and animal life, because not all things that can elicit a serious immune response should get one. For example: A bee sting. A serious immune response to that could kill you and in people seriously-allergic that’s a real risk. So why don’t most people get a serious immune response?
As it turns out they sort of do, but its focuses in one sort of IgG build, IgG4, which suppresses the cascade of events that cause the body to go after the thing in question and destroy it, along with all the side effects that produces (fever, serious inflammation, etc.)
Well, when you get Covid typically IgG3 is the one that neutralizes most of the virus. IgG1 and 2 do some of the work, but most of it is done by IgG3. You’re not supposed to build an IgG4 response, and with natural infection without vaccination you don’t, thus there’s no inhibition and your response is and remains effective at neutralizing whatever it is. Typical vaccines (e.g. measles) elicit a response that looks exactly like an actual infection because that’s how they’re designed and intended; they use the whole virus and their intent is to make your body think it is being invaded by the real deal and respond as it would to the real deal.
None of the western world Covid jabs do this on purpose. They were all crafted to use only part of the virus, and the reason for that is past experience trying to create coronavirus vaccines all ended in failure with many of them producing wild enhancement of the infection instead of protection and in animal testing reliably killed the animals. Thus the decision was made without long-term safety and efficacy testing to use only the spike, with the idea that doing so would prevent the bad outcome.
They were wrong; it didn’t prevent the bad outcome but instead shifted it in ways that were wildly insidious and unforeseen.
As it turns out what is now in the data is that IgG3, which the component that provides most of the protection against Covid is down to a flat zero by the time you take the third shot while IgG4 which causes the body to tolerate the infection and not clear it skyrockets from nothing prior to the second shot to being extremely high for the third and subsequent.
This was never detected in the trials because they didn’t look and it takes time to find it because the conversion only happens when you get infected after you’re jabbed. So if you only test for three months and don’t look at the IgG profile you’ll never see it happen, never mind that until you boost the data is that while its detectable after the second shot (and thus could have been detected if they bothered to look) the response curve is exponential and its the third one that basically zeros the IgG3 response if, following the first booster, you get infected again — and you will as neutralization from the booster itself wanes.
Remember, IgG4 causes the body to tolerate the infection rather than attack and clear it.
This turns you into a walking virus mutation and production factory, a source of infection to everyone around you and, to the extent that the virus does direct damage to your body systems, and we know the spike does, it also is likely to lead to very severe long-term problems that look like other conditions. Nobody is looking for spike damage specifically in, for example, heart attacks, strokes and pulmonary embolisms, never mind the possibility of potentiating cancer by suppressing immune response if that suppression and tolerance goes beyond Covid, and it very well might. If that’s not bad enough everyone that got jabbed has the same profile of response where the normal situation is that responses differ in different people because our body systems operate slightly differently (we’re all genetically unique.)
Now who’s most-likely to have had the most number of jabs and thus are walking around tolerating infections and giving them to others? Health care workers! And who goes to the hospital or doctor? Compromised individuals who can least-withstand infections. Gee, that was smart, right?
What’s worse is that we do not know if this is local to Covid or even just coronaviruses. It might not be. We may now have created a couple hundred million people in the US alone who have coded their immune systems to tolerate certain proteins that are common across all manner of respiratory viruses and worse, if its not local to viruses to be more-susceptible to cancer and other immune-sensitive problems with no way to reverse the effects!
If you recall I pointed out very early on in this thing that jabbing people with a non-sterilizing immune product, which these jabs all are, was wildly irresponsible because at minimum it would likely cause a decrease in symptoms and thus make it more likely rather than less that you’d go out and infect other people unknowingly. That was and remains correct however what nobody knew because we didn’t look is that said non-sterilizing jabs had an even worse outcome in that they shift your immune response from elimination to tolerance so now, particularly after the third, you are likely to carry and not eliminate covid which makes you a literal Typhoid Mary, and if that’s not enough we have no idea if this effect is local to Covid itself (which, in the world of Omicron isn’t so awful as Omicron doesn’t seem to be killing many people) but it may extend to influenza and even RSV, and is even more-likely to extend to the other two common beta coronaviruses OC43 and HKU1.
And finally, this may be permanent in those people who took the jabs. We don’t know.
But what we do know, factually, is that when you get infected with Covid post Jab #3 your neutralizing antibody product is a statistical zero while your “tolerance” antibody production shoots the moon. This is exactly backward from what you want to happen and we are now left trying to figure out exactly how badly you screwed both yourself and others.